From Business: Travel Happy® with Drury Hotels. You have enough to worry about while you're traveling. Let us take a few things off your plate, so you can focus on the good stuff. Breakfast,…

From Business: Settle in for a relaxing stay at the Sikeston’s newest hotel. Our Hampton Inn Sikeston hotel is located off Highway 60 and Interstate 55, just minutes from historic downtown…

"It was my first time staying at a Best Western and I enjoyed it. I was suprised to see how much space we had in our room. But, it was a good amount of space for the cost of the…"

From Business: Large illuminating lights and contemporary decor welcome you to the Holiday Inn Express & Suites Sikeston. Our hotel’s address in Sikeston, MO surrounds you with fun and nearby…

From Business: This wyndham Hotels affiliate is a all Suite property with large bedrooms and living rooms, 2 LED television in each room, located near restaurants, Sikeston Jaycee Bootheel…

From Business: See why so many travelers make Comfort Inn & Suites Sikeston their hotel of choice when visiting Sikeston. Providing an ideal mix of value, comfort and convenience, it offers a…

From Business: Find comfort at the newly-opened TownePlace Suites Sikeston. Our pet friendly hotel in Sikeston, MO? is conveniently located off Highway 60 and Interstate 55, close to historic…

From Business: Our brand-new hotel in Sikeston, MO is conveniently located off Highway 60 and Interstate 55, very close to historic downtown and a short walk to a variety of shops and…