From Business: Travel Happy® with Drury Hotels. You have enough to worry about while you're traveling. Let us take a few things off your plate, so you can focus on the good stuff. Breakfast,…

"It was my first time staying at a Best Western and I enjoyed it. I was suprised to see how much space we had in our room. But, it was a good amount of space for the cost of the…"

From Business: This wyndham Hotels affiliate is a all Suite property with large bedrooms and living rooms, 2 LED television in each room, located near restaurants, Sikeston Jaycee Bootheel…

From Business: See why so many travelers make Comfort Inn & Suites Sikeston their hotel of choice when visiting Sikeston. Providing an ideal mix of value, comfort and convenience, it offers a…

From Business: Settle in for a relaxing stay at the Sikeston’s newest hotel. Our Hampton Inn Sikeston hotel is located off Highway 60 and Interstate 55, just minutes from historic downtown…

From Business: Large illuminating lights and contemporary decor welcome you to the Holiday Inn Express & Suites Sikeston. Our hotel’s address in Sikeston, MO surrounds you with fun and nearby…

From Business: See why so many travelers make Eagle Inn their motel of choice when visiting Charleston. Providing an ideal mix of value, comfort and convenience, it offers a budget friendly…

From Business: Find comfort at the newly-opened TownePlace Suites Sikeston. Our pet friendly hotel in Sikeston, MO? is conveniently located off Highway 60 and Interstate 55, close to historic…

From Business: Our brand-new hotel in Sikeston, MO is conveniently located off Highway 60 and Interstate 55, very close to historic downtown and a short walk to a variety of shops and…