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      Lodging in Sikeston, MO

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      1. Super 8 by Wyndham Sikeston/Miner Area

      Super 8 by Wyndham Sikeston/Miner Area
      573-471-7944Call NowVisit Website
      Directions
      LodgingHotelsMotels

      2609 E Malone Ave, Sikeston, MO 63801

      OPEN 24 HOURS
      YP
      54 Years
      in Business

      2. Days Inn Sikeston

      Days Inn Sikeston
      573-471-3930Call NowVisit Website
      Directions
      LodgingMotelsHotels

      1330 S Main St, Sikeston, MO 63801

      OPEN 24 HOURS

      From Business: Days Inn is a provider of hospitality services and accommodation facility. Based in Sikeston, Mo., it offers daybreak breakfast items, such as Minute Maid juices, Kellogg's…

      3. TownePlace Suites by Marriott Sikeston

      TownePlace Suites by Marriott Sikeston
      573-930-0500Call NowVisit Website
      Directions
      LodgingHotelsCorporate Lodging

      1239 S Commerce Dr, Sikeston, MO 63801

      From Business: Find comfort at the newly-opened TownePlace Suites Sikeston. Our pet friendly hotel in Sikeston, MO? is conveniently located off Highway 60 and Interstate 55, close to historic…

      YP
      2 Years
      in Business

      4. Fairfield Inn & Suites

      Fairfield Inn & Suites
      573-919-7200Call NowVisit Website
      Directions
      LodgingHotelsCorporate Lodging

      1239 S Commerce Dr, Sikeston, MO 63801

      From Business: Our brand-new hotel in Sikeston, MO is conveniently located off Highway 60 and Interstate 55, very close to historic downtown and a short walk to a variety of shops and…

      YP
      2 Years
      in Business

      5. Holiday Inn Express & Suites Sikeston by IHG

      Holiday Inn Express & Suites Sikeston by IHG
      573-475-9522Call NowVisit Website
      Directions
      LodgingHotelsWedding Chapels & Ceremonies

      115 Hospitality Dr, Sikeston, MO 63801

      OPEN 24 HOURS

      From Business: Large illuminating lights and contemporary decor welcome you to the Holiday Inn Express & Suites Sikeston. Our hotel’s address in Sikeston, MO surrounds you with fun and nearby…

      YP
      12 Years
      in Business

      6. Hampton Inn Sikeston

      Hampton Inn Sikeston
      573-621-4100Call NowVisit Website
      Directions
      LodgingHotels

      1240 S Commerce Dr, Sikeston, MO 63801

      OPEN 24 HOURS

      From Business: Settle in for a relaxing stay at the Sikeston’s newest hotel. Our Hampton Inn Sikeston hotel is located off Highway 60 and Interstate 55, just minutes from historic downtown…

      YP
      8 Years
      in Business

      7. Comfort Inn & Suites Sikeston I-55

      Comfort Inn & Suites Sikeston I-55
      573-472-0197Call NowVisit Website
      Directions
      LodgingMotelsHotels

      109 Matthews Ln, Sikeston, MO 63801

      From Business: See why so many travelers make Comfort Inn & Suites Sikeston their hotel of choice when visiting Sikeston. Providing an ideal mix of value, comfort and convenience, it offers a…

      8. Pear Tree Inn Sikeston

      Pear Tree Inn Sikeston
      573-471-4100Call NowVisit Website
      Directions
      LodgingMotels

      2602 E Malone Ave, Sikeston, MO 63801

      From Business: Pear Tree Inn by Drury provides an outstanding balance of quality, amenities and value. Guests can enjoy a free breakfast daily, free wireless Internet access in all rooms and…

      9. Drury Inn & Suites Sikeston

      Drury Inn & Suites Sikeston
      573-472-2299Call NowVisit Website
      Directions
      LodgingHotels

      2608 E Malone Ave, Sikeston, MO 63801

      OPEN 24 HOURS

      From Business: Travel Happy® with Drury Hotels. You have enough to worry about while you're traveling. Let us take a few things off your plate, so you can focus on the good stuff. Breakfast,…

      Amenities:
      Wheelchair accessible

      10. Country Yard Inn And Suites

      Country Yard Inn And Suites
      573-471-7400Call NowVisit Website
      Directions
      Lodging

      110 S Interstate Dr I-55 At Us-62/East Malone Street Exit #67, Sikeston, MO 63801

      OPEN 24 HOURS

      From Business: Motel 6 Sikeston is an excellent choice for travelers visiting Sikeston, offering a budget friendly environment alongside many helpful amenities designed to enhance your stay.…

      11. Best Western Plus Sikeston

      Best Western Plus Sikeston
      573-481-9500Call NowVisit Website
      Directions
      5.0
      5.0
      LodgingHotels

      120 S Interstate Dr, Sikeston, MO 63801

      OPEN 24 HOURS

      "It was my first time staying at a Best Western and I enjoyed it. I was suprised to see how much space we had in our room. But, it was a good amount of space for the cost of the…"

      YP
      16 Years
      in Business

      14. Motel 6

      Motel 6
      573-471-7400Call NowVisit Website
      Directions
      LodgingMotelsHotels

      110 S Interstate Dr, Sikeston, MO 63801

      YP
      26 Years
      in Business

      16. Eagle Inn Charleston

      Eagle Inn Charleston
      573-683-3900Call NowVisit Website
      Directions
      LodgingMotelsHotels

      2811 E Marshall St, Charleston, MO 63834

      OPEN 24 HOURS

      From Business: See why so many travelers make Eagle Inn their motel of choice when visiting Charleston. Providing an ideal mix of value, comfort and convenience, it offers a budget friendly…

      19. Grace Inn

      Grace Inn
      573-649-5616Call NowVisit Website
      Directions
      LodgingBed & Breakfast & Inns

      127 Baker Ln, East Prairie, MO 63845

      CLOSED NOW:8:00 am - 5:00 pm
      Amenities:
      Wheelchair accessible

      We found 20 results for Lodging in or near Sikeston, MO.They also appear in other related business categories including Hotels, Motels, and Corporate Lodging. 4 of the rated businesses have 4+ star ratings.