What'sNearbyTM

What are you looking for?

Close Search
      We apologize for the inconvenience

      The people search feature on Superpages.com is temporarily unavailable. You can still search for people on yellowpages.com since Yellow Pages and Superpages are part of one company.

      You will be automatically re-directed to People Search on yellowpages.com in .

      Gary S. Firestein, MD

      Add to Favorites
      Be the first to review!
      Physicians & Surgeons, Rheumatology (Arthritis)

      200 W Arbor Dr, San Diego, CA 92103

      858-822-0480

      OPEN NOW: 
      Today: 9:00 am - 5:00 pm
      Amenities:
      Wheelchair accessible
      Call

      REVIEWS write reviewWrite a Review

      Be the first to review!
      First-classBetter than mostAbout what I expectedNot the worst...Disappointing
      DETAILS
      General Info
      Dr. Firesteins research efforts have focused on the pathogenesis of rheumatoid arthritis (RA). His laboratory helped define the synovial cytokine profile of RA and demonstrated the dominance of macrophage and fibroblast products as opposed to the expected T cell cytokines. These studies contributed to the development of the highly effective anti-TNF approaches in RA. Recently, Dr. Firestein has focused his attention on synoviocyte transformation in RA as a mechanism of joint destruction. His group was the first to describe somatic mutations in the p53 tumor suppressor genes in the RA synovium. The mutations were subsequently demonstrated to be dominant negative and increased the cartilage invasiveness of these cells. Dr. Firesteins laboratory has also worked extensively on metalloproteinase and cytokine gene regulation in synoviocytes by MAP kinases and NF-kB as well as on novel gene therapy approaches to RA.UC San Diego Health LinksFor more information, see http://health.ucsd.edu/specialties/arthritis/Pages/default.aspx.
      Hours
      Regular Hours
      Mon - Fri:
      Category
      Physicians & Surgeons, Rheumatology (Arthritis)
      Neighborhoods
      Hillcrest, Western San Diego
      Other Information

      Specialties: Internal Medicine

      Suggest an Edit
      Data provided by one or more of the following: Thryv, Data Axle, Yext.